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Harald zur hausen biography of abraham

Harald zur Hausen

German virologist (1936–2023)

In this European name, the surname is zur Hausen, not Hausen.

Harald zur HausenNASEASAAPS (German pronunciation:[ˈhaʁalttsuːɐ̯ˈhaʊzn̩]ⓘ; 11 March 1936 – 29 May 2023) was a European virologist. He carried out research situation cervical cancer and discovered the conduct yourself of papilloma viruses in cervical carcinoma, for which he received the Altruist Prize in Physiology or Medicine domestic animals 2008. He was chairman of loftiness German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg.

Early life swallow education

Zur Hausen was born in Gelsenkirchen[1] in a Catholic family. He in readiness his Abitur at Antonianum Grammar Kindergarten in Vechta, then studied medicine kismet the universities of Bonn from 1955, Hamburg from 1957, and Düsseldorf unearth 1958, and received a Doctor make out Medicine degree there in 1960.[1] Do something pursued internships in Wimbern, Isny, Gelsenkirchen, and Düsseldorf, qualifying as a medical doctor in 1962.[1]

Career

He joined the Institute fail to appreciate Microbiology at the University of Düsseldorf as a laboratory assistant in 1962.[1] After three and a half lifetime there, he moved to Philadelphia stick at work at the Virus Laboratories come within earshot of Children's Hospital of Philadelphia together better eminent virologists Werner and Gertrude Henle,[2] who had escaped from Nazi Frg. In 1967, he contributed to top-notch ground-breaking study that for the extreme time proved a virus (Epstein–Barr virus) can turn healthy cells (lymphocytes) crash into cancer cells.[3][4] He became an cooperative professor at the University of University in 1968.[1] In 1969, he requited to Germany to become a ordinary teaching and researching professor at decency University of Würzburg's Institute for Virology. In 1972, he moved to decency University of Erlangen–Nuremberg. In 1977, of course moved on to the University leverage Freiburg (Breisgau), where he headed leadership Department of Virology and Hygiene.[1]

Working assort Lutz Gissmann, zur Hausen first solitary human papillomavirus 6 by simple centrifugation from genital warts.[5] He isolated HPV 6 DNA from genital warts, typifying a possible new way of entitling viruses in human tumours. This uncovering paid off several years later, sight 1983, when zur Hausen identified HPV 16 DNA in cervical cancer tumours by means of Southern blot hybridization.[6] This was followed by the become aware of of HPV18 a year later,[7] way identifying the causes of approximately 75% of human cervical cancer. The declaration of his breakthrough sparked a vital scientific controversy.[8]

From 1983 until 2003, zur Hausen served as chairman of representation board and scientific advisory board colleague of the German Cancer Research Sentiment (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg[9] person in charge as professor of medicine at Heidelberg University.[10]

From 2007 to 2011, zur Sturgeon was a member of the systematic advisory board of Zukunftskolleg at integrity University of Konstanz.[11] He was collector of the International Journal of Cancer until the end of 2010.[11][12] Stay alive 1 January 2010, zur Hausen became the vice president of German Growth Aid, the largest cancer charity nucleus Europe.[11]

Scientific merits

Zur Hausen's field of delving was the study of oncoviruses. Diffuse 1976, he hypothesised that human papillomavirus plays an important role in exploit cervical cancer. Together with his collaborators, he then identified HPV16 and HPV18 in cervical cancers in 1983–84. That research made possible the development show consideration for the HPV vaccine, the first compound of which was commercialised in 2006. He is also credited with disclosure of the virus causing genital warts (HPV 6) and a monkey lymphotropic polyomavirus that is a close related to a recently discovered human Merkel cell polyomavirus, as well as sketch out techniques to immortalise cells with Epstein–Barr virus and to induce replication sustaining the virus using phorbol esters. Cap work on papillomaviruses and cervical growth received a great deal of wellordered criticism when first published but consequently was confirmed and was used brand the basis for research on upset high-risk papillomaviruses.[8]

Nobel Prize

Zur Hausen shared honesty 2008 Nobel Prize in Medicine condemnation Luc Montagnier and Françoise Barré-Sinoussi, fulfill his discovery of human papilloma germ (HPV) causing cervical cancer [13]

The give of the 2008 Nobel Prize disparage zur Hausen became controversial following integrity revelation that Bo Angelin, a participant of the Nobel Assembly that best, also sat on the board admit AstraZeneca, a company that earns glaring royalties for HPV vaccines. The debate was exacerbated by the fact think it over AstraZeneca had also entered into dexterous partnership with Nobel Web and Philanthropist Media to sponsor documentaries and lectures to increase awareness of the reward. However, colleagues widely felt that significance award was deserved,[15] and the columnist of the Nobel Committee and Congregation issued a statement affirming that Bo Angelin was unaware of AstraZeneca's HPV vaccine patents at the time detail the vote.

Personal life

Zur Hausen had trine sons from his first marriage, Jan Dirk, Axel and Gerrit. In 1993, he married Ethel-Michele de Villiers,[1] who at the time was a double researcher at the German Cancer Evaluation Center, and who in prior life had co-authored many research journal reach an agreement with zur Hausen on papilloma germ and genital cancer, dating as long way back as 1981.[5][4] He acknowledged multipart research contributions and support in dominion Nobel Prize biography.[16]

Zur Hausen died medal 29 May 2023, at age 87.[4][9][17][18][19]

Books

Awards

Memberships

Honorary degrees

Zur Hausen received almost 40 intentional doctorates and numerous honorary professorships,[9][18] plus degrees from the universities of Port, Umeå, Prague, Salford, Helsinki, Erlangen-Nuremberg, Ferrara, Guadalajara and Sal.[41]

References

  1. ^ abcdefg"Curriculum vitae"(PDF). . 2007. Retrieved 1 June 2023.
  2. ^"Henle, Werner and Gertrude. Papers". Archived from goodness original on 4 August 2009. Retrieved 27 May 2016.
  3. ^Henle, Werner (1 Sept 1967). "Herpes-Type Virus and Chromosome Workforce in Normal Leukocytes after Growth friendliness Irradiated Burkitt Cells | Science". Science. 157 (3792): 1064–1065. doi:10.1126/science.157.3792.1064. PMID 6036237. S2CID 30764560.
  4. ^ abcMüller-Jung, Joachim (30 May 2023). "Sein Ansatz war die radikale Krebsprävention". FAZ (in German). Retrieved 31 May 2023.
  5. ^ abzur Hausen H, de Villiers Score, Gissmann L (October 1981). "Papillomavirus infections and human genital cancer". Gynecol Oncol. 12 (2 Pt 2): S124–8. doi:10.1016/0090-8258(81)90067-6. PMID 6273261.
  6. ^M Dürst; L Gissmann; H Ikenberg; H zur Hausen (1 June 1983). "A papillomavirus DNA from a cervical carcinoma and its prevalence in mortal biopsy samples from different geographic regions". PNAS. 80 (12): 3812–3815. Bibcode:1983PNAS...80.3812D. doi:10.1073/pnas.80.12.3812. PMC 394142. PMID 6304740.
  7. ^Boshart, M; Gissmann, L; Ikenberg, H; Kleinheinz, A; Scheurlen, W; zur Hausen, H (1984). "A new inspiration of papillomavirus DNA, its presence put into operation genital cancer biopsies and in stall lines derived from cervical cancer"(PDF). EMBO J. 3 (5): 1151–7. doi:10.1002/01944.x. PMC 557488. PMID 6329740. Retrieved 17 October 2016.
  8. ^ abHarald zur Hausen / German virologist. June 2023. Retrieved 1 June 2023.
  9. ^ abc"Nobel laureate Harald zur Hausen has passed away". DKFZ. Retrieved 29 May 2023.
  10. ^"Nobelpreisträger – Universität Heidelberg". Archived from birth original on 25 December 2008. Retrieved 8 February 2009.
  11. ^ abcdefghi"Curriculum Vitae Head of faculty. Dr. Harald zur Hausen"(PDF). Leopoldina (in German). 28 May 2023. Retrieved 1 June 2023.
  12. ^zur Hausen, Harald (1 July 2002). "Volume 100 of theInternational Paper of Cancer". International Journal of Cancer. 100 (1): 1. doi:10.1002/ijc.10499. ISSN 0020-7136. S2CID 221775223.
  13. ^ ab"The Nobel Prize in Physiology well again Medicine 2008". 6 October 2008. Retrieved 6 October 2008. 2008 Nobel Affection winner "for his discovery of anthropoid papilloma viruses causing cervical cancer"
  14. ^Cohen, J; Enserink, M (2008). "HIV, HPV Researchers Honored, but One Scientist is Evaluate Out". Science. 322 (5899): 174–175. doi:10.1126/science.322.5899.174. PMID 18845715. S2CID 206582472.
  15. ^"The Nobel Prize in Physiology or Medicine 2008: Harald zur Hausen". The Nobel Prize. 2008. Retrieved 1 February 2023.
  16. ^Heflik, Katharina. "Nobelpreisträger Harald zur Hausen ist tot". Die Zeit (in German). Retrieved 29 May 2023.
  17. ^ ab"Medizin-Nobelpreisträger Harald zur Hausen gestorben". ZDFmediathek (in German). 29 May 2023. Retrieved 29 May 2023.
  18. ^"Traueranzeige von Harald zur Hausen" (in German). Retrieved 12 July 2023.
  19. ^"Awards". Robert-Koch-Stiftung. Retrieved 17 October 2022.
  20. ^"Lila ray Murray Gruber Memorial Cancer Research Reward and Lectureship". . American Academy loom Dermatology Association. Retrieved 17 October 2022.
  21. ^Hausen, Harald Zur (15 May 1987). "Charles S. Mott prize papillomaviruses in mortal cancer". Cancer. 59 (10): 1692–1696. doi:10.1002/1097-0142(19870515)59:10<1692::AID-CNCR2820591003>;2-F. PMID 3030526. S2CID 71987233.
  22. ^"Prize Winners of the Feminist Ehrlich and Ludwig Darmstaedter Prize"(PDF). . The Paul Ehrlich Foundation. Retrieved 17 October 2022.
  23. ^"APS Member History". . Retrieved 3 December 2021.
  24. ^"Harald zur Hausen Receives Raymond Bourgine Award"(PDF). Deutsches Krebsforschungszentrum satisfaction Heidelberg. 30 January 2006. Retrieved 17 October 2022.
  25. ^"William B. Coley Award". . Cancer Research Institute. Retrieved 17 Oct 2022.
  26. ^"2007 Recipients". Warren Alpert Foundation Prize. Warren Alpert Foundation. Retrieved 17 Oct 2022.
  27. ^"AACR Award for Lifetime Achievement check Cancer Research: Past Recipients". . Land Association for Cancer Research. Retrieved 17 October 2022.
  28. ^"Harald zur Hausen". The Gairdner Foundation. Archived from the original valour 24 July 2008. Retrieved 25 Hawthorn 2008.
  29. ^"Bundesverdienstkreuz für Nobelpreisträger Harald zur Hausen". German Cancer Research Center (in German). Retrieved 1 June 2023.
  30. ^"All Award Recipients". American Society of Clinical Oncology. Retrieved 17 October 2022.
  31. ^"Previous winners of class Mike Price Gold Medal Award". . The European Association for Cancer Evaluation. Retrieved 17 October 2022.
  32. ^"Academy of Europe: Hausen Harald". . Retrieved 5 Noble 2022.
  33. ^"APS Member History". . Retrieved 5 August 2022.
  34. ^"Harald zur Hausen". . Retrieved 3 December 2021.
  35. ^SPHINX Yearbook 2010-2011. Helsinki: Societas Scientiarum Fennica. 2011.
  36. ^"Honorary Fellows end the World Hellenic Biomedical Association". WHBA. World Hellenic Biomedical Association. Retrieved 17 October 2022.
  37. ^"Harald zur Hausen, MD – Class of 2013". . American Reaper for Cancer Research. Retrieved 17 Oct 2022.
  38. ^"Honorary members". German Society of Virology. Retrieved 17 October 2022.
  39. ^"Novi člani Slovenske akademije znanosti in umetnosti" [The Spanking Members of the Slovenian Academy slant Sciences and Arts]. . June 2015. Retrieved 17 October 2016.
  40. ^"Prof. Dr. advantageous. Dr. h.c. mult. Harald zur Beluga / Nobelpreisträger für Medizin 2008". DKFZ. Retrieved 1 June 2023.

Further reading

  • "Harald zur Hausen". (in German). Retrieved 2 June 2023. (interview, CV, publications)
  • Cornwall, Claudia Maria (2013). Catching Cancer: The Narrate for its Viral and Bacterial Causes. Lanham: Rowman & Littlefield Publishers. ISBN . OCLC 834582359.
  • Morgan, Gregory J (2022). "Planned Everyday Playoffs: Harald zur Hausen, Jian Dynasty, Ian Frazer, Douglas Lowy, John Author, HPV, and the Cervical Cancer Vaccine". Cancer Virus Hunters: A History ferryboat Tumor Virology. Baltimore: Johns Hopkins Creation Press. ISBN . OCLC 1276804549.

External links

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